Term Information

Accession
GO:0016581
Name
NuRD complex
Ontology
cellular_component
Synonyms
NRD complex, nucleosome remodeling and histone deacetylation complex, Mi-2 complex
Alternate IDs
None
Definition
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. Source: PMID:10589671, PMID:11743021, PMID:17289569
Comment
None
History
See term history for GO:0016581 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of NuRD complex (GO:0016581)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NuRD complex [is_a relation] is_a  transcription regulator complex (GO:0005667)
NuRD complex [is_a relation] is_a  CHD-type complex (GO:0090545)
NuRD complex [is_a relation] is_a  histone deacetylase complex (GO:0000118)
Children of NuRD complex (GO:0016581)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
SHREC complex (GO:0070824) [is_a relation] is_a  NuRD complex
SHREC2 complex (GO:0110129) [is_a relation] is_a  NuRD complex
None.