Term Information

Accession
GO:0016513
Name
core-binding factor complex
Ontology
cellular_component
Synonyms
CBF complex, AML1 complex, PEPB2 complex
Alternate IDs
None
Definition
A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit. Source: PMID:8497254, PMID:15156179
Comment
None
History
See term history for GO:0016513 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of core-binding factor complex (GO:0016513)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
core-binding factor complex [is_a relation] is_a  RNA polymerase II transcription regulator complex (GO:0090575)

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None.