Planteome: Term Details for "gene silencing" (GO:0016458)

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Term Information

Accession: GO:0016458
Name: gene silencing
Ontology: biological_process
Synonyms: long-term maintenance of gene inactivation
Alternate IDs: None
Definition: Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression. Source: GOC:dph, GOC:tb, GOC:jid, GOC:dos
Comment: This is a rather broad grouping term. While it was originally defined for long-term, heritable, epigenetic effects, short term effects on expression mediated by RNA are also frequently referred to as gene silencing, and are grouped under this class.
History: See term history for GO:0016458 at QuickGO
Subset: goslim_drosophila; goslim_pir
Related: Link to all annotated objects annotated to gene silencing.; Link to all direct and indirect annotations to gene silencing.; Link to all direct and indirect annotations download (limited to first 10,000) for gene silencing.
Feedback: Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0008150 biological_process
GO:0065007 biological regulation
BFO:0000001 entity
GO:0008152 metabolic process
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0048519 negative regulation of biological process
BFO:0000003 occurrent
GO:0071704 organic substance metabolic process
GO:0019222 regulation of metabolic process
GO:0010467 gene expression
GO:0009892 negative regulation of metabolic process
BFO:0000015 process
GO:0060255 regulation of macromolecule metabolic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010468 regulation of gene expression
GO:0009987 cellular process
GO:0010629 negative regulation of gene expression
GO:0016458 gene silencing
GO:0006342 chromatin silencing
GO:0031047 gene silencing by RNA
GO:0010978 gene silencing involved in chronological cell aging
GO:0098795 mRNA cleavage involved in gene silencing
GO:0060969 negative regulation of gene silencing
GO:0016441 posttranscriptional gene silencing
GO:0060968 regulation of gene silencing

Parents of gene silencing (GO:0016458)

subject	relation	object
gene silencing	is_a	negative regulation of gene expression (GO:0010629)
gene silencing	is_a	cellular process (GO:0009987)

Children of gene silencing (GO:0016458)

subject	relation	object
posttranscriptional gene silencing (GO:0016441)	is_a	gene silencing
chromatin silencing (GO:0006342)	is_a	gene silencing
regulation of gene silencing (GO:0060968)	RO:0002211	gene silencing
gene silencing by RNA (GO:0031047)	is_a	gene silencing
gene silencing involved in chronological cell aging (GO:0010978)	is_a	gene silencing
negative regulation of gene silencing (GO:0060969)	RO:0002212	gene silencing
mRNA cleavage involved in gene silencing (GO:0098795)	BFO:0000050	gene silencing

Wikipedia: Gene_silencing