Term Information

Accession
GO:0016442
Name
RISC complex
Ontology
cellular_component
Synonyms
RNA-induced silencing complex, miRNP complex, micro-ribonucleoprotein complex
Alternate IDs
GO:0035068
Definition
A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. Source: PMID:10749213, PMID:15145345
Comment
None
History
See term history for GO:0016442 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of RISC complex (GO:0016442)
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RISC complex [is_a relation] is_a  RNAi effector complex (GO:0031332)

This term has no children.