Term Information

Accession
GO:0008705
Name
methionine synthase activity
Ontology
molecular_function
Synonyms
5-methyltetrahydrofolate-homocysteine S-methyltransferase activity, 5-methyltetrahydrofolate--homocysteine S-methyltransferase activity, 5-methyltetrahydrofolate--homocysteine transmethylase activity, 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity, B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity, B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity, MetH, N(5)-methyltetrahydrofolate methyltransferase activity, N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity, N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity, N-methyltetrahydrofolate:L-homocysteine methyltransferase activity, N5-methyltetrahydrofolate methyltransferase activity, N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity, N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity, cobalamin-dependent methionine synthase activity, methionine synthase (cobalamin-dependent) activity, methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity, tetrahydrofolate methyltransferase activity, tetrahydropteroylglutamate methyltransferase activity, tetrahydropteroylglutamic methyltransferase activity, vitamin B12 methyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine. Source: EC:2.1.1.13, RHEA:11172
Comment
None
History
See term history for GO:0008705 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of methionine synthase activity (GO:0008705)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
methionine synthase activity [BFO:0000050 relation] BFO:0000050  methionine biosynthetic process (GO:0009086)
methionine synthase activity [is_a relation] is_a  5-methyltetrahydrofolate-dependent methyltransferase activity (GO:0042084)
methionine synthase activity [is_a relation] is_a  S-methyltransferase activity (GO:0008172)

This term has no children.

EC
2.1.1.13
KEGG_REACTION
R00946
MetaCyc
HOMOCYSMETB12-RXN
Reactome
R-HSA-3149539
R-HSA-174374
RHEA
11172