Term Information

Accession
GO:0008518
Name
folate:monoatomic anion antiporter activity
Ontology
molecular_function
Synonyms
reduced folate carrier activity, reduced folate transmembrane transporter activity, reduced folate transporter, folate:anion antiporter activity
Alternate IDs
None
Definition
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF. Source: GOC:mtg_transport, PMID:24745983, PMID:21568705, TC:2.A.48
Comment
None
History
See term history for GO:0008518 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of folate:monoatomic anion antiporter activity (GO:0008518)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
folate:monoatomic anion antiporter activity [is_a relation] is_a  antiporter activity (GO:0015297)
folate:monoatomic anion antiporter activity [is_a relation] is_a  active monoatomic ion transmembrane transporter activity (GO:0022853)
folate:monoatomic anion antiporter activity [is_a relation] is_a  monoatomic anion transmembrane transporter activity (GO:0008509)
folate:monoatomic anion antiporter activity [is_a relation] is_a  folic acid transmembrane transporter activity (GO:0008517)

This term has no children.

TC
2.A.48