Term Information

Accession
GO:0008424
Name
glycoprotein 6-alpha-L-fucosyltransferase activity
Ontology
molecular_function
Synonyms
FucT, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity, GDP-L-fucose--glycoprotein fucosyltransferase activity, GDP-fucose--glycoprotein fucosyltransferase activity, GDPfucose-glycoprotein fucosyltransferase activity, guanosine diphosphofucose--glycoprotein fucosyltransferase activity, glycoprotein fucosyltransferase activity
Alternate IDs
None
Definition
Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H+. Source: RHEA:12985, EC:2.4.1.68
Comment
None
History
See term history for GO:0008424 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of glycoprotein 6-alpha-L-fucosyltransferase activity (GO:0008424)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
glycoprotein 6-alpha-L-fucosyltransferase activity [BFO:0000050 relation] BFO:0000050  N-glycan fucosylation (GO:0036071)
glycoprotein 6-alpha-L-fucosyltransferase activity [is_a relation] is_a  alpha-(1->6)-fucosyltransferase activity (GO:0046921)
glycoprotein 6-alpha-L-fucosyltransferase activity [is_a relation] is_a  catalytic activity, acting on a glycoprotein (GO:0140103)

This term has no children.

EC
2.4.1.68
KEGG_REACTION
R05988
MetaCyc
2.4.1.68-RXN
Reactome
R-HSA-1028788
R-HSA-9696980
RHEA
12985