Term Information

Accession
GO:0008386
Name
cholesterol monooxygenase (side-chain-cleaving) activity
Ontology
molecular_function
Synonyms
C27-side chain cleavage enzyme, cholesterol 20-22-desmolase activity, cholesterol C(20-22) desmolase activity, cholesterol C20-22 desmolase activity, cholesterol desmolase activity, cholesterol side-chain cleavage enzyme activity, cholesterol side-chain-cleaving enzyme activity, cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving), cytochrome P-450scc, cytochrome p450scc, desmolase, steroid 20-22, enzymes, cholesterol side-chain-cleaving, Cyp11a1, cytochrome P-450(scc) activity, cytochrome p450(scc) activity, steroid 20-22 desmolase activity, steroid 20-22-lyase activity
Alternate IDs
None
Definition
Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O. Source: EC:1.14.15.6
Comment
None
History
See term history for GO:0008386 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of cholesterol monooxygenase (side-chain-cleaving) activity (GO:0008386)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
cholesterol monooxygenase (side-chain-cleaving) activity [is_a relation] is_a  steroid hydroxylase activity (GO:0008395)
cholesterol monooxygenase (side-chain-cleaving) activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen (GO:0016713)

This term has no children.