Term Information

Accession
GO:0007091
Name
metaphase/anaphase transition of mitotic cell cycle
Ontology
biological_process
Synonyms
metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, mitotic metaphase/anaphase transition
Alternate IDs
None
Definition
The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. Source: PMID:10465783, GOC:mtg_cell_cycle
Comment
None
History
See term history for GO:0007091 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of metaphase/anaphase transition of mitotic cell cycle (GO:0007091)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
metaphase/anaphase transition of mitotic cell cycle [is_a relation] is_a  metaphase/anaphase transition of cell cycle (GO:0044784)
metaphase/anaphase transition of mitotic cell cycle [BFO:0000050 relation] BFO:0000050  mitotic cell cycle (GO:0000278)
metaphase/anaphase transition of mitotic cell cycle [is_a relation] is_a  mitotic cell cycle phase transition (GO:0044772)
Children of metaphase/anaphase transition of mitotic cell cycle (GO:0007091)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of mitotic metaphase/anaphase transition (GO:0045842) [RO:0002213 relation] RO:0002213  metaphase/anaphase transition of mitotic cell cycle
negative regulation of mitotic metaphase/anaphase transition (GO:0045841) [RO:0002212 relation] RO:0002212  metaphase/anaphase transition of mitotic cell cycle
regulation of mitotic metaphase/anaphase transition (GO:0030071) [RO:0002211 relation] RO:0002211  metaphase/anaphase transition of mitotic cell cycle
None.