Term Information

Accession
GO:0006352
Name
DNA-templated transcription initiation
Ontology
biological_process
Synonyms
DNA-dependent RNA polymerase complex assembly at promoter, DNA-dependent transcription, initiation, DNA-templated transcription, initiation, initiation of DNA-dependent transcription, initiation of transcription, DNA-dependent, transcription initiation factor activity, transcription initiation, DNA-dependent, transcription initiation from bacterial-type RNA polymerase promoter
Alternate IDs
GO:0001123
Definition
The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. Source: PMID:18280161, GOC:txnOH, GOC:jid
Comment
Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
History
See term history for GO:0006352 at QuickGO
Subset
goslim_yeast
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of DNA-templated transcription initiation (GO:0006352)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA-templated transcription initiation [is_a relation] is_a  RNA biosynthetic process (GO:0032774)
DNA-templated transcription initiation [BFO:0000050 relation] BFO:0000050  DNA-templated transcription (GO:0006351)
Children of DNA-templated transcription initiation (GO:0006352)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transcription initiation at RNA polymerase III promoter (GO:0006384) [is_a relation] is_a  DNA-templated transcription initiation
regulation of DNA-templated transcription initiation (GO:2000142) [RO:0002211 relation] RO:0002211  DNA-templated transcription initiation
negative regulation of DNA-templated transcription initiation (GO:2000143) [RO:0002212 relation] RO:0002212  DNA-templated transcription initiation
transcription initiation at mitochondrial promoter (GO:0006391) [is_a relation] is_a  DNA-templated transcription initiation
transcription preinitiation complex assembly (GO:0070897) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription initiation
DNA-templated transcriptional start site selection (GO:0001173) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription initiation
positive regulation of DNA-templated transcription initiation (GO:2000144) [RO:0002213 relation] RO:0002213  DNA-templated transcription initiation
transcription initiation at RNA polymerase II promoter (GO:0006367) [is_a relation] is_a  DNA-templated transcription initiation
DNA-templated transcription open complex formation (GO:0001112) [BFO:0000050 relation] BFO:0000050  DNA-templated transcription initiation
transcription initiation at RNA polymerase I promoter (GO:0006361) [is_a relation] is_a  DNA-templated transcription initiation
None.