Term Information

Accession
GO:0006273
Name
lagging strand elongation
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork. Source: GOC:mah, ISBN:0815316194, ISBN:071673706X
Comment
None
History
See term history for GO:0006273 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of lagging strand elongation (GO:0006273)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
lagging strand elongation [BFO:0000051 relation] BFO:0000051  DNA replication, synthesis of RNA primer (GO:0006269)
lagging strand elongation [BFO:0000051 relation] BFO:0000051  DNA replication, removal of RNA primer (GO:0043137)
lagging strand elongation [is_a relation] is_a  DNA strand elongation involved in DNA replication (GO:0006271)
Children of lagging strand elongation (GO:0006273)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA replication, Okazaki fragment processing (GO:0033567) [BFO:0000050 relation] BFO:0000050  lagging strand elongation
lagging strand initiation (GO:0090629) [BFO:0000050 relation] BFO:0000050  lagging strand elongation
mitotic DNA replication lagging strand elongation (GO:1903459) [is_a relation] is_a  lagging strand elongation
None.