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eukaryotic translation initiation factor 3 complex

Term Information

Accession
GO:0005852
Name
eukaryotic translation initiation factor 3 complex
Ontology
cellular_component
Synonyms
eIF-3, eIF3
Alternate IDs
None
Definition
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs. Source: PMID:15904532
Comment
None
History
See term history for GO:0005852 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of eukaryotic translation initiation factor 3 complex (GO:0005852)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
eukaryotic translation initiation factor 3 complex [is_a relation] is_a  protein-containing complex (GO:0032991)
eukaryotic translation initiation factor 3 complex [BFO:0000050 relation] BFO:0000050  cytoplasm (GO:0005737)
Children of eukaryotic translation initiation factor 3 complex (GO:0005852)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
eukaryotic translation initiation factor 3 complex, eIF3e (GO:0071540) [is_a relation] is_a  eukaryotic translation initiation factor 3 complex
eukaryotic translation initiation factor 3 complex, eIF3m (GO:0071541) [is_a relation] is_a  eukaryotic translation initiation factor 3 complex
None.