CBC, NCBP-NIP1 complex, mRNA cap binding complex, snRNA cap binding complex
Alternate IDs
None
Definition
A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.
Source:PMID:16043498
Comment
Note that this complex can be found in the cytoplasm as well as the nucleus.