Term Information

Accession
GO:0005834
Name
heterotrimeric G-protein complex
Ontology
cellular_component
Synonyms
heterotrimeric G-protein GTPase activity, heterotrimeric G-protein GTPase, alpha-subunit, heterotrimeric G-protein GTPase, beta-subunit, heterotrimeric G-protein GTPase, gamma-subunit
Alternate IDs
None
Definition
Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. Source: ISBN:0198547684
Comment
See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.
History
See term history for GO:0005834 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of heterotrimeric G-protein complex (GO:0005834)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
heterotrimeric G-protein complex [is_a relation] is_a  plasma membrane protein complex (GO:0098797)
heterotrimeric G-protein complex [BFO:0000050 relation] BFO:0000050  extrinsic component of cytoplasmic side of plasma membrane (GO:0031234)
heterotrimeric G-protein complex [is_a relation] is_a  GTPase complex (GO:1905360)

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None.