Planteome: Term Details for "anaphase-promoting complex" (GO:0005680)

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Term Information

Accession: GO:0005680
Name: anaphase-promoting complex
Ontology: cellular_component
Synonyms: anaphase promoting complex, cyclosome, APC
Alternate IDs: None
Definition: A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B. Source: GOC:jh, GOC:vw, PMID:10465783, PMID:10611969
Comment: Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.
History: See term history for GO:0005680 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to anaphase-promoting complex.; Link to all direct and indirect annotations to anaphase-promoting complex.; Link to all direct and indirect annotations download (limited to first 10,000) for anaphase-promoting complex.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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GO:0005575 cellular_component
GO:0110165 cellular anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043226 organelle
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0043231 intracellular membrane-bounded organelle
GO:0140535 intracellular protein-containing complex
GO:0005634 nucleus
GO:1990234 transferase complex
GO:0140513 nuclear protein-containing complex
GO:0000151 ubiquitin ligase complex
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0000152 nuclear ubiquitin ligase complex
GO:0005680 anaphase-promoting complex

Parents of anaphase-promoting complex (GO:0005680)

subject	relation	object
anaphase-promoting complex	is_a	cullin-RING ubiquitin ligase complex (GO:0031461)
anaphase-promoting complex	is_a	nuclear ubiquitin ligase complex (GO:0000152)

This term has no children.

Wikipedia: Anaphase-promoting_complex