Term Information

Accession
GO:0005220
Name
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
Ontology
molecular_function
Synonyms
IP3 receptor activity, InsP3 receptor, inositol-1,4,5-trisphosphate receptor activity
Alternate IDs
GO:0008095
Definition
Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts. Source: GOC:signaling, PMID:8660280, Wikipedia:Inositol_trisphosphate_receptor, GOC:mah
Comment
None
History
See term history for GO:0005220 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0005220)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [BFO:0000051 relation] BFO:0000051  inositol 1,4,5 trisphosphate binding (GO:0070679)
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [is_a relation] is_a  calcium-release channel activity (GO:0015278)
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [BFO:0000050 relation] BFO:0000050  inositol phosphate-mediated signaling (GO:0048016)
Children of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0005220)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031585) [RO:0002211 relation] RO:0002211  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031587) [RO:0002213 relation] RO:0002213  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031586) [RO:0002212 relation] RO:0002212  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels (GO:0098695) [is_a relation] is_a  inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
None.