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death receptor activity

Term Information

Accession
GO:0005035
Name
death receptor activity
Ontology
molecular_function
Synonyms
apoptosis-activating receptor activity
Alternate IDs
None
Definition
Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death. Source: GOC:BHF, GOC:bf, PMID:10209153, GOC:mtg_apoptosis, GOC:ecd, GOC:rl
Comment
None
History
See term history for GO:0005035 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of death receptor activity (GO:0005035)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
death receptor activity [is_a relation] is_a  transmembrane signaling receptor activity (GO:0004888)
death receptor activity [BFO:0000050 relation] BFO:0000050  programmed cell death (GO:0012501)
Children of death receptor activity (GO:0005035)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
death receptor agonist activity (GO:0038177) [RO:0002213 relation] RO:0002213  death receptor activity
TRAIL receptor activity (GO:0036463) [is_a relation] is_a  death receptor activity
tumor necrosis factor receptor activity (GO:0005031) [is_a relation] is_a  death receptor activity
None.