Term Information

Accession
GO:0005024
Name
transforming growth factor beta receptor activity
Ontology
molecular_function
Synonyms
TGF-beta receptor activity, TGFbeta receptor activity, TGFbeta-activated receptor activity, TGFbetaR, transforming growth factor beta-activated receptor activity
Alternate IDs
None
Definition
Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Source: GOC:signaling, GOC:mah
Comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
History
See term history for GO:0005024 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of transforming growth factor beta receptor activity (GO:0005024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta receptor activity [is_a relation] is_a  transmembrane receptor protein serine/threonine kinase activity (GO:0004675)
Children of transforming growth factor beta receptor activity (GO:0005024)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
transforming growth factor beta receptor activity, type III (GO:0070123) [is_a relation] is_a  transforming growth factor beta receptor activity
transforming growth factor beta receptor activity, type II (GO:0005026) [is_a relation] is_a  transforming growth factor beta receptor activity
transforming growth factor beta receptor activity, type I (GO:0005025) [is_a relation] is_a  transforming growth factor beta receptor activity
None.