Term Information

Accession
GO:0004950
Name
chemokine receptor activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria. Source: GOC:signaling, PMID:12183377, PMID:8662823, GOC:BHF, IUPHAR_GPCR:1280, Wikipedia:Chemokine, GOC:rl
Comment
None
History
See term history for GO:0004950 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of chemokine receptor activity (GO:0004950)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
chemokine receptor activity [is_a relation] is_a  G protein-coupled chemoattractant receptor activity (GO:0001637)
chemokine receptor activity [BFO:0000050 relation] BFO:0000050  chemokine-mediated signaling pathway (GO:0070098)
chemokine receptor activity [is_a relation] is_a  cytokine receptor activity (GO:0004896)
chemokine receptor activity [BFO:0000051 relation] BFO:0000051  chemokine binding (GO:0019956)
Children of chemokine receptor activity (GO:0004950)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
C-X3-C chemokine receptor activity (GO:0016495) [is_a relation] is_a  chemokine receptor activity
C-X-C chemokine receptor activity (GO:0016494) [is_a relation] is_a  chemokine receptor activity
C-C chemokine receptor activity (GO:0016493) [is_a relation] is_a  chemokine receptor activity
None.