Planteome: Term Details for "uracil DNA N-glycosylase activity" (GO:0004844)

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Term Information

Accession: GO:0004844
Name: uracil DNA N-glycosylase activity
Ontology: molecular_function
Synonyms: uracil-DNA glycosylase activity
Alternate IDs: None
Definition: Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine. Source: PMID:9224623, GOC:pr, GOC:elh
Comment: None
History: See term history for GO:0004844 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to uracil DNA N-glycosylase activity.; Link to all direct and indirect annotations to uracil DNA N-glycosylase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for uracil DNA N-glycosylase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0140097 catalytic activity, acting on DNA
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0019104 DNA N-glycosylase activity
GO:0097506 deaminated base DNA N-glycosylase activity
GO:0004844 uracil DNA N-glycosylase activity
GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity
GO:0017065 single-strand selective uracil DNA N-glycosylase activity

Parents of uracil DNA N-glycosylase activity (GO:0004844)

subject	relation	object
uracil DNA N-glycosylase activity	is_a	deaminated base DNA N-glycosylase activity (GO:0097506)

Children of uracil DNA N-glycosylase activity (GO:0004844)

subject	relation	object
single-strand selective uracil DNA N-glycosylase activity (GO:0017065)	is_a	uracil DNA N-glycosylase activity
G/U mismatch-specific uracil-DNA glycosylase activity (GO:0043739)	is_a	uracil DNA N-glycosylase activity

EC: 3.2.2.27
https: //github.com/geneontology/go-ontology/issues/25051
Reactome: R-HSA-110215; R-HSA-110217