Term Information

Accession
GO:0004707
Name
MAP kinase activity
Ontology
molecular_function
Synonyms
ERK1, mitogen activated kinase activity, ATP:protein phosphotransferase (MAPKK-activated) activity, ERK, ERK2, MAPK, mitogen-activated protein kinase activity, MAP kinase 1 activity, MAP kinase 2 activity, MBP kinase I activity, MBP kinase II activity, SAP kinase activity, SAPK, extracellular signal-regulated kinase activity, myelin basic protein kinase activity, stress-activated kinase activity, stress-activated protein kinase activity
Alternate IDs
GO:0008338, GO:0008339, GO:0016908, GO:0016909
Definition
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli. Source: ISBN:0198547684, GOC:ma
Comment
None
History
See term history for GO:0004707 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of MAP kinase activity (GO:0004707)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
MAP kinase activity [is_a relation] is_a  protein serine/threonine kinase activity (GO:0004674)
MAP kinase activity [BFO:0000050 relation] BFO:0000050  MAPK cascade (GO:0000165)
Children of MAP kinase activity (GO:0004707)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of MAP kinase activity (GO:0043406) [RO:0002213 relation] RO:0002213  MAP kinase activity
negative regulation of MAP kinase activity (GO:0043407) [RO:0002212 relation] RO:0002212  MAP kinase activity
regulation of MAP kinase activity (GO:0043405) [RO:0002211 relation] RO:0002211  MAP kinase activity
JUN kinase activity (GO:0004705) [is_a relation] is_a  MAP kinase activity