Planteome: Term Details for "cyclin-dependent protein serine/threonine kinase activity" (GO:0004693)

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Term Information

Accession: GO:0004693
Name: cyclin-dependent protein serine/threonine kinase activity
Ontology: molecular_function
Synonyms: CDK activity, CDK, catalytic subunit activity, cyclin-dependent protein kinase, intrinsic catalyst activity, ATP:cyclin phosphotransferase activity, CDK, Cdk-activating protein kinase activity, cdk-activating kinase activity, D-type cyclin kinase activity, cdc2 kinase activity, cyclin D-cdk6 kinase activity, cyclin D-dependent kinase activity, cyclin E kinase activity, cyclin-A associated kinase activity, cyclin-dependent kinase 6 activity, cyclin-dependent kinase-2 activity, cyclin-dependent kinase-4 activity, neuronal cdc2-like kinase activity, cyclin-dependent kinase activity, cyclin-dependent protein kinase activity
Alternate IDs: GO:0016537
Definition: Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Source: GOC:rn, PMID:7877684, GOC:pr, PMID:9841670
Comment: This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
History: See term history for GO:0004693 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to cyclin-dependent protein serine/threonine kinase activity.; Link to all direct and indirect annotations to cyclin-dependent protein serine/threonine kinase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for cyclin-dependent protein serine/threonine kinase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0003824 catalytic activity
BFO:0000015 process
GO:0065007 biological regulation
GO:0003674 molecular_function
GO:0016740 transferase activity
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0140096 catalytic activity, acting on a protein
GO:0007049 cell cycle
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0050794 regulation of cellular process
GO:0004672 protein kinase activity
GO:0051726 regulation of cell cycle
GO:0097472 cyclin-dependent protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity

Parents of cyclin-dependent protein serine/threonine kinase activity (GO:0004693)

subject	relation	object
cyclin-dependent protein serine/threonine kinase activity	is_a	cyclin-dependent protein kinase activity (GO:0097472)
cyclin-dependent protein serine/threonine kinase activity	is_a	protein serine/threonine kinase activity (GO:0004674)

Children of cyclin-dependent protein serine/threonine kinase activity (GO:0004693)

subject	relation	object
negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736)	RO:0002212	cyclin-dependent protein serine/threonine kinase activity
regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079)	RO:0002211	cyclin-dependent protein serine/threonine kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737)	RO:0002213	cyclin-dependent protein serine/threonine kinase activity

EC: 2.7.11.22
MetaCyc: 2.7.11.22-RXN
Reactome: R-HSA-5195402; R-HSA-188390; R-HSA-68944; R-HSA-6793661; R-HSA-4088024; R-HSA-187916; R-HSA-9686521; R-HSA-9624800; R-HSA-2245218; R-HSA-2294600; R-HSA-6797606; R-HSA-5244669; R-HSA-380278; R-HSA-6805109; R-HSA-69005; R-HSA-2172183; R-HSA-187948; R-HSA-2220971; R-HSA-2990882; R-HSA-69227; R-HSA-1226095; R-HSA-1226094; R-HSA-2468293; R-HSA-174251; R-HSA-187520; R-HSA-174132; R-HSA-2984220; R-HSA-9009282; R-HSA-174079; R-HSA-1912391; R-HSA-2430533; R-HSA-9008412; R-HSA-4086410; R-HSA-3788705; R-HSA-5692755; R-HSA-2514854; R-HSA-69754; R-HSA-180047; R-HSA-69756; R-HSA-187959; R-HSA-174122; R-HSA-2468287