Term Information

Accession
GO:0004668
Name
protein-arginine deiminase activity
Ontology
molecular_function
Synonyms
peptidylarginine deiminase activity, protein-L-arginine iminohydrolase activity
Alternate IDs
None
Definition
Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent. Source: PMID:27393304
Comment
None
History
See term history for GO:0004668 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of protein-arginine deiminase activity (GO:0004668)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
protein-arginine deiminase activity [is_a relation] is_a  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO:0016813)
protein-arginine deiminase activity [BFO:0000050 relation] BFO:0000050  histone modification (GO:0016570)
Children of protein-arginine deiminase activity (GO:0004668)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone arginine deiminase activity (GO:0140794) [is_a relation] is_a  protein-arginine deiminase activity