Term Information

Accession
GO:0004506
Name
squalene monooxygenase activity
Ontology
molecular_function
Synonyms
squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity, squalene 2,3-oxidocyclase activity, squalene epoxidase activity, squalene hydroxylase activity, squalene oxydocyclase activity, squalene-2,3-epoxidase activity, squalene-2,3-epoxide cyclase activity
Alternate IDs
None
Definition
Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+. Source: RHEA:25282
Comment
None
History
See term history for GO:0004506 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of squalene monooxygenase activity (GO:0004506)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
squalene monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709)

This term has no children.

EC
1.14.14.17
KEGG_REACTION
R02874
MetaCyc
SQUALENE-MONOOXYGENASE-RXN
Reactome
R-HSA-191299
RHEA
25282