Planteome: Term Details for "tyrosinase activity" (GO:0004503)

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Term Information

Accession: GO:0004503
Name: tyrosinase activity
Ontology: molecular_function
Synonyms: L-tyrosine monooxygenase activity, monophenol monooxygenase activity, monophenol oxygenase, N-acetyl-6-hydroxytryptophan oxidase activity, catecholase, chlorogenic acid oxidase activity, chlorogenic oxidase activity, cresolase activity, dopa oxidase, monophenol monooxidase activity, monophenol oxidase activity, monophenolase activity, o-diphenol oxidase activity, o-diphenol oxidoreductase, o-diphenol:O2 oxidoreductase activity, prophenol oxidase activity, prophenoloxidase activity, tyrosine-dopa oxidase activity, phenol oxidase activity, phenolase activity, pyrocatechol oxidase
Alternate IDs: None
Definition: Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates. Source: PMID:4965136, RHEA:18117
Comment: In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.
History: See term history for GO:0004503 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to tyrosinase activity.; Link to all direct and indirect annotations to tyrosinase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for tyrosinase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0004497 monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
GO:0004503 tyrosinase activity
GO:0032772 negative regulation of tyrosinase activity
GO:0032773 positive regulation of tyrosinase activity
GO:0032771 regulation of tyrosinase activity

Parents of tyrosinase activity (GO:0004503)

subject	relation	object
tyrosinase activity	is_a	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen (GO:0016716)

Children of tyrosinase activity (GO:0004503)

subject	relation	object
regulation of tyrosinase activity (GO:0032771)	RO:0002211	tyrosinase activity
positive regulation of tyrosinase activity (GO:0032773)	RO:0002213	tyrosinase activity
negative regulation of tyrosinase activity (GO:0032772)	RO:0002212	tyrosinase activity

EC: 1.14.18.1
MetaCyc: MONOPHENOL-MONOOXYGENASE-RXN