Planteome: Term Details for "malate dehydrogenase (decarboxylating) (NADP+) activity" (GO:0004473)

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Term Information

Accession: GO:0004473
Name: malate dehydrogenase (decarboxylating) (NADP+) activity
Ontology: molecular_function
Synonyms: 'malic' enzyme, (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating), L-malate:NADP oxidoreductase activity, NADP-linked decarboxylating malic enzyme, NADP-malic enzyme activity, NADP-specific malate dehydrogenase activity, NADP-specific malic enzyme, malate dehydrogenase (NADP, decarboxylating), malate dehydrogenase (decarboxylating, NADP)
Alternate IDs: None
Definition: Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+. Source: EC:1.1.1.40
Comment: For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'.
History: See term history for GO:0004473 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to malate dehydrogenase (decarboxylating) (NADP+) activity.; Link to all direct and indirect annotations to malate dehydrogenase (decarboxylating) (NADP+) activity.; Link to all direct and indirect annotations download (limited to first 10,000) for malate dehydrogenase (decarboxylating) (NADP+) activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016615 malate dehydrogenase activity
GO:0004470 malic enzyme activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity
GO:1903219 negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity
GO:1903220 positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity
GO:1903218 regulation of malate dehydrogenase (decarboxylating) (NADP+) activity

Parents of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:0004473)

subject	relation	object
malate dehydrogenase (decarboxylating) (NADP+) activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
malate dehydrogenase (decarboxylating) (NADP+) activity	is_a	malic enzyme activity (GO:0004470)

Children of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:0004473)

subject	relation	object
negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903219)	RO:0002212	malate dehydrogenase (decarboxylating) (NADP+) activity
regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903218)	RO:0002211	malate dehydrogenase (decarboxylating) (NADP+) activity
positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity (GO:1903220)	RO:0002213	malate dehydrogenase (decarboxylating) (NADP+) activity

EC: 1.1.1.40
KEGG_REACTION: R00216
MetaCyc: MALIC-NADP-RXN
Reactome: R-HSA-9012349; R-HSA-9012036
RHEA: 18253