Term Information

Accession
GO:0004464
Name
leukotriene-C4 synthase activity
Ontology
molecular_function
Synonyms
(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening), (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming), LTC(4) synthase activity, LTC(4) synthetase activity, LTC4 synthase activity, LTC4 synthetase activity, leukotriene A(4):glutathione S-leukotrienyltransferase activity, leukotriene A4:glutathione S-leukotrienyltransferase activity, leukotriene C(4) synthetase activity, leukotriene C4 synthetase activity, leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)
Alternate IDs
None
Definition
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). Source: EC:4.4.1.20, RHEA:17617
Comment
Note that this function was EC:2.5.1.37.
History
See term history for GO:0004464 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of leukotriene-C4 synthase activity (GO:0004464)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
leukotriene-C4 synthase activity [is_a relation] is_a  carbon-sulfur lyase activity (GO:0016846)

This term has no children.

EC
4.4.1.20
KEGG_REACTION
R03059
MetaCyc
LEUKOTRIENE-C4-SYNTHASE-RXN
Reactome
R-HSA-266050
RHEA
17617