Planteome: Term Details for "hydroxymethylglutaryl-CoA synthase activity" (GO:0004421)

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Term Information

Accession: GO:0004421
Name: hydroxymethylglutaryl-CoA synthase activity
Ontology: molecular_function
Synonyms: (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity, 3-hydroxy-3-methylglutaryl CoA synthetase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthase activity, 3-hydroxy-3-methylglutaryl coenzyme A synthetase activity, 3-hydroxy-3-methylglutaryl-CoA synthase activity, 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity, HMG-CoA synthase activity, acetoacetyl coenzyme A transacetase activity, acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), beta-hydroxy-beta-methylglutaryl-CoA synthase activity, hydroxymethylglutaryl coenzyme A synthase activity, hydroxymethylglutaryl coenzyme A-condensing enzyme, hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity
Alternate IDs: None
Definition: Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H2O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H+. Source: RHEA:10188
Comment: Note that this function was formerly EC:4.1.3.5.
History: See term history for GO:0004421 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to hydroxymethylglutaryl-CoA synthase activity.; Link to all direct and indirect annotations to hydroxymethylglutaryl-CoA synthase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for hydroxymethylglutaryl-CoA synthase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
GO:0004421 hydroxymethylglutaryl-CoA synthase activity

Parents of hydroxymethylglutaryl-CoA synthase activity (GO:0004421)

subject	relation	object
hydroxymethylglutaryl-CoA synthase activity	is_a	acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)

This term has no children.

EC: 2.3.3.10
KEGG_REACTION: R01978
MetaCyc: HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
Reactome: R-HSA-191323; R-HSA-73918
RHEA: 10188