Planteome: Term Details for "hydroxymethylbilane synthase activity" (GO:0004418)

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Term Information

Accession: GO:0004418
Name: hydroxymethylbilane synthase activity
Ontology: molecular_function
Synonyms: (4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity, (4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing), HMB-synthase activity, porphobilinogen ammonia-lyase (polymerizing), porphobilinogen deaminase activity, porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing), pre-uroporphyrinogen synthase activity, uroporphyrinogen synthase activity, uroporphyrinogen synthetase activity, uroporphyrinogen I synthase activity, uroporphyrinogen I synthetase activity
Alternate IDs: None
Definition: Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4. Source: RHEA:13185, EC:2.5.1.61
Comment: Note that this function was formerly EC:4.3.1.8.
History: See term history for GO:0004418 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to hydroxymethylbilane synthase activity.; Link to all direct and indirect annotations to hydroxymethylbilane synthase activity.; Link to all direct and indirect annotations download (limited to first 10,000) for hydroxymethylbilane synthase activity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
BFO:0000015 process
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0004418 hydroxymethylbilane synthase activity

Parents of hydroxymethylbilane synthase activity (GO:0004418)

subject	relation	object
hydroxymethylbilane synthase activity	is_a	transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765)

This term has no children.

EC: 2.5.1.61
KEGG_REACTION: R00084
MetaCyc: OHMETHYLBILANESYN-RXN
Reactome: R-HSA-189406
RHEA: 13185