Term Information

Accession
GO:0004407
Name
histone deacetylase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes. Source: RHEA:58196, PMID:9893272
Comment
None
History
See term history for GO:0004407 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of histone deacetylase activity (GO:0004407)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
histone deacetylase activity [is_a relation] is_a  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
histone deacetylase activity [is_a relation] is_a  protein lysine deacetylase activity (GO:0033558)
histone deacetylase activity [is_a relation] is_a  histone modifying activity (GO:0140993)
Children of histone deacetylase activity (GO:0004407)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of histone deacetylase activity (GO:1901725) [RO:0002211 relation] RO:0002211  histone deacetylase activity
histone H3K deacetylase activity (GO:0141050) [is_a relation] is_a  histone deacetylase activity
NAD-independent histone deacetylase activity (GO:0045129) [is_a relation] is_a  histone deacetylase activity
NAD-dependent histone deacetylase activity (GO:0017136) [is_a relation] is_a  histone deacetylase activity
negative regulation of histone deacetylase activity (GO:1901726) [RO:0002212 relation] RO:0002212  histone deacetylase activity
positive regulation of histone deacetylase activity (GO:1901727) [RO:0002213 relation] RO:0002213  histone deacetylase activity
histone H4K deacetylase activity (GO:0141051) [is_a relation] is_a  histone deacetylase activity