Term Information

Accession
GO:0003878
Name
ATP citrate synthase activity
Ontology
molecular_function
Synonyms
ATP-citrate (pro-S)-lyase activity, ATP citrate (pro-S)-lyase activity, ATP-citrate (pro-S-)-lyase activity, ATP-citric lyase activity, ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity, ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating), acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating], acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity, acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating), adenosine triphosphate citrate lyase activity, citrate cleavage enzyme activity, citrate-ATP lyase activity, citric cleavage enzyme activity
Alternate IDs
GO:0046913
Definition
Catalysis of the reaction: acetyl-CoA + ADP + H+ + oxaloacetate + phosphate = ATP + citrate + CoA. Source: RHEA:21160
Comment
Note that this function was formerly EC:4.1.3.8. Note that this term has a MetaCyc pathway reference as the pathway only has a single step.
History
See term history for GO:0003878 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

Filter results

Loading...
pending...
Parents of ATP citrate synthase activity (GO:0003878)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ATP citrate synthase activity [is_a relation] is_a  acyltransferase activity, acyl groups converted into alkyl on transfer (GO:0046912)
Children of ATP citrate synthase activity (GO:0003878)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of ATP citrate synthase activity (GO:2000985) [RO:0002213 relation] RO:0002213  ATP citrate synthase activity
negative regulation of ATP citrate synthase activity (GO:2000984) [RO:0002212 relation] RO:0002212  ATP citrate synthase activity
regulation of ATP citrate synthase activity (GO:2000983) [RO:0002211 relation] RO:0002211  ATP citrate synthase activity
EC
2.3.3.8
KEGG_REACTION
R00352
MetaCyc
ATP-CITRATE-PRO-S--LYASE-RXN
PWY-5172
Reactome
R-HSA-75848
RHEA
21160