Term Information

Accession
GO:0002480
Name
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
Ontology
biological_process
Synonyms
TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent exogenous peptide antigen processing and presentation via MHC class I, exogenous peptide antigen processing and presentation via MHC class I, TAP-independent, cross presentation, cross-presentation
Alternate IDs
None
Definition
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules. Source: PMID:15224093, GOC:add, PMID:15771591, PMID:16181335
Comment
None
History
See term history for GO:0002480 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (GO:0002480)
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antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent [is_a relation] is_a  antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)

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