Term Information

Accession
GO:0002416
Name
IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
Ontology
biological_process
Synonyms
IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor, IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor
Alternate IDs
None
Definition
The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals. Source: ISBN:0781735149, GOC:add, ISBN:081533642X
Comment
None
History
See term history for GO:0002416 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor (GO:0002416)
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IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor [is_a relation] is_a  immunoglobulin transcytosis in epithelial cells (GO:0002414)

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None.