Term Information

Accession
GO:0002291
Name
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Ontology
biological_process
Synonyms
T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
Alternate IDs
None
Definition
The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response. Source: ISBN:0781735149, GOC:add
Comment
None
History
See term history for GO:0002291 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:0002291)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [is_a relation] is_a  T cell activation involved in immune response (GO:0002286)
Children of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:0002291)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001190) [RO:0002213 relation] RO:0002213  T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001189) [RO:0002212 relation] RO:0002212  T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001188) [RO:0002211 relation] RO:0002211  T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
None.