Term Information

Accession
GO:0002255
Name
tissue kallikrein-kinin cascade
Ontology
biological_process
Synonyms
glandular kallikrein-kinin cascade
Alternate IDs
None
Definition
A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability. Source: PMID:11842287, PMID:14501145, GOC:add
Comment
None
History
See term history for GO:0002255 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of tissue kallikrein-kinin cascade (GO:0002255)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tissue kallikrein-kinin cascade [is_a relation] is_a  kinin cascade (GO:0002254)
Children of tissue kallikrein-kinin cascade (GO:0002255)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of tissue kallikrein-kinin cascade (GO:0002547) [RO:0002213 relation] RO:0002213  tissue kallikrein-kinin cascade
negative regulation of tissue kallikrein-kinin cascade (GO:0002546) [RO:0002212 relation] RO:0002212  tissue kallikrein-kinin cascade
regulation of tissue kallikrein-kinin cascade (GO:0002382) [RO:0002211 relation] RO:0002211  tissue kallikrein-kinin cascade
None.