A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
Source:PMID:14724296,
PMID:16495340
Comment
Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.