Term Information

Accession
GO:0002029
Name
desensitization of G protein-coupled receptor signaling pathway
Ontology
biological_process
Synonyms
desensitisation of G-protein coupled receptor protein signalling pathway, desensitization of G-protein coupled receptor protein signaling pathway
Alternate IDs
None
Definition
The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway. Source: PMID:8396717
Comment
None
History
See term history for GO:0002029 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of desensitization of G protein-coupled receptor signaling pathway (GO:0002029)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
desensitization of G protein-coupled receptor signaling pathway [is_a relation] is_a  negative adaptation of signaling pathway (GO:0022401)
desensitization of G protein-coupled receptor signaling pathway [is_a relation] is_a  negative regulation of G protein-coupled receptor signaling pathway (GO:0045744)
Children of desensitization of G protein-coupled receptor signaling pathway (GO:0002029)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
G protein-coupled receptor internalization (GO:0002031) [BFO:0000050 relation] BFO:0000050  desensitization of G protein-coupled receptor signaling pathway
desensitization of G protein-coupled receptor signaling pathway by arrestin (GO:0002032) [is_a relation] is_a  desensitization of G protein-coupled receptor signaling pathway
inhibitory G protein-coupled receptor phosphorylation (GO:0002030) [BFO:0000050 relation] BFO:0000050  desensitization of G protein-coupled receptor signaling pathway
None.