Planteome: Term Details for "T cell mediated cytotoxicity" (GO:0001913)

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Term Information

Accession: GO:0001913
Name: T cell mediated cytotoxicity
Ontology: biological_process
Synonyms: T cell mediated apoptosis, T cell mediated cell death, T cell mediated cell killing, T lymphocyte mediated cytotoxicity, T-cell mediated apoptosis, T-cell mediated cell death, T-cell mediated cell killing, T-cell mediated cytotoxicity, T-lymphocyte mediated cytotoxicity, T cell mediated cytolysis
Alternate IDs: None
Definition: The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. Source: GOC:pr, ISBN:0781735149, GOC:add, PMID:11911826
Comment: Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not.
History: See term history for GO:0001913 at QuickGO
Subset: None
Related: Link to all annotated objects annotated to T cell mediated cytotoxicity.; Link to all direct and indirect annotations to T cell mediated cytotoxicity.; Link to all direct and indirect annotations download (limited to first 10,000) for T cell mediated cytotoxicity.
Feedback: Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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BFO:0000001 entity
BFO:0000003 occurrent
GO:0008150 biological_process
GO:0002376 immune system process
BFO:0000015 process
GO:0050896 response to stimulus
GO:0006955 immune response
GO:0002250 adaptive immune response
GO:0009987 cellular process
GO:0002252 immune effector process
GO:0002443 leukocyte mediated immunity
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0001906 cell killing
GO:0002449 lymphocyte mediated immunity
GO:0001909 leukocyte mediated cytotoxicity
GO:0002456 T cell mediated immunity
GO:0001913 T cell mediated cytotoxicity
GO:0043316 cytotoxic T cell degranulation
GO:0001915 negative regulation of T cell mediated cytotoxicity
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0001914 regulation of T cell mediated cytotoxicity
GO:0002419 T cell mediated cytotoxicity directed against tumor cell target

Parents of T cell mediated cytotoxicity (GO:0001913)

subject	relation	object
T cell mediated cytotoxicity	is_a	T cell mediated immunity (GO:0002456)
T cell mediated cytotoxicity	is_a	leukocyte mediated cytotoxicity (GO:0001909)

Children of T cell mediated cytotoxicity (GO:0001913)

subject	relation	object
T cell mediated cytotoxicity directed against tumor cell target (GO:0002419)	is_a	T cell mediated cytotoxicity
negative regulation of T cell mediated cytotoxicity (GO:0001915)	RO:0002212	T cell mediated cytotoxicity
cytotoxic T cell degranulation (GO:0043316)	BFO:0000050	T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity (GO:0001916)	RO:0002213	T cell mediated cytotoxicity
regulation of T cell mediated cytotoxicity (GO:0001914)	RO:0002211	T cell mediated cytotoxicity

T cell mediated cytotoxicity

Term Information

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Parents of T cell mediated cytotoxicity (GO:0001913)

Children of T cell mediated cytotoxicity (GO:0001913)

None.