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type IIa hypersensitivity

Term Information

Accession
GO:0001794
Name
type IIa hypersensitivity
Ontology
biological_process
Synonyms
None
Alternate IDs
None
Definition
An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell. Source: ISBN:0781735149, GOC:add
Comment
Note that some type IIb hypersensitivity responses (GO:0001795) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIa hypersensitivity.
History
See term history for GO:0001794 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of type IIa hypersensitivity (GO:0001794)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
type IIa hypersensitivity [is_a relation] is_a  type II hypersensitivity (GO:0002445)
Children of type IIa hypersensitivity (GO:0001794)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
regulation of type IIa hypersensitivity (GO:0001796) [RO:0002211 relation] RO:0002211  type IIa hypersensitivity
positive regulation of type IIa hypersensitivity (GO:0001798) [RO:0002213 relation] RO:0002213  type IIa hypersensitivity
negative regulation of type IIa hypersensitivity (GO:0001797) [RO:0002212 relation] RO:0002212  type IIa hypersensitivity
antibody-dependent cellular cytotoxicity (GO:0001788) [is_a relation] is_a  type IIa hypersensitivity
None.