Term Information

Accession
GO:0001771
Name
immunological synapse formation
Ontology
biological_process
Synonyms
formation of immunological synapse
Alternate IDs
None
Definition
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction. Source: PMID:11244041, GOC:mgi_curators, PMID:11376330
Comment
None
History
See term history for GO:0001771 at QuickGO
Subset
None
Feedback
Contact the Planteome feedback if you find mistakes or have concerns about the data you find here.
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of immunological synapse formation (GO:0001771)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
immunological synapse formation [is_a relation] is_a  cell-cell recognition (GO:0009988)
immunological synapse formation [BFO:0000050 relation] BFO:0000050  lymphocyte activation (GO:0046649)
Children of immunological synapse formation (GO:0001771)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
negative regulation of immunological synapse formation (GO:2000521) [RO:0002212 relation] RO:0002212  immunological synapse formation
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation (GO:2000526) [BFO:0000050 relation] BFO:0000050  immunological synapse formation
positive regulation of immunological synapse formation (GO:2000522) [RO:0002213 relation] RO:0002213  immunological synapse formation
regulation of immunological synapse formation (GO:2000520) [RO:0002211 relation] RO:0002211  immunological synapse formation
None.