Term Information

Accession
GO:0001648
Name
proteinase-activated receptor activity
Ontology
molecular_function
Synonyms
protease-activated receptor activity, proteinase activated receptor activity
Alternate IDs
None
Definition
A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it. Source: GOC:mah, PMID:33742547, PMID:11356985
Comment
None
History
See term history for GO:0001648 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of proteinase-activated receptor activity (GO:0001648)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
proteinase-activated receptor activity [is_a relation] is_a  G protein-coupled peptide receptor activity (GO:0008528)
Children of proteinase-activated receptor activity (GO:0001648)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
positive regulation of proteinase activated receptor activity (GO:1900278) [RO:0002213 relation] RO:0002213  proteinase-activated receptor activity
regulation of proteinase activated receptor activity (GO:1900276) [RO:0002211 relation] RO:0002211  proteinase-activated receptor activity
negative regulation of proteinase activated receptor activity (GO:1900277) [RO:0002212 relation] RO:0002212  proteinase-activated receptor activity
thrombin-activated receptor activity (GO:0015057) [is_a relation] is_a  proteinase-activated receptor activity
None.