serotonin receptor activity, coupled via Gq/11, 5-HT2 receptor activity
Alternate IDs
None
Definition
Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
Source:PMID:18571247,
PMID:18703043,
GOC:bf,
GOC:mah