Term Information

Accession
GO:0000978
Name
RNA polymerase II cis-regulatory region sequence-specific DNA binding
Ontology
molecular_function
Synonyms
RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II promoter proximal region sequence-specific DNA binding, RNA polymerase II proximal promoter sequence-specific DNA binding, RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding
Alternate IDs
GO:0000980
Definition
Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. Source: GOC:txnOH-2018
Comment
Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer".
History
See term history for GO:0000978 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase II cis-regulatory region sequence-specific DNA binding [is_a relation] is_a  RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)
RNA polymerase II cis-regulatory region sequence-specific DNA binding [is_a relation] is_a  cis-regulatory region sequence-specific DNA binding (GO:0000987)
Children of RNA polymerase II cis-regulatory region sequence-specific DNA binding (GO:0000978)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending (GO:0044377) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
GC-box binding (GO:0140728) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
vitamin D response element binding (GO:0070644) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
serum response element binding (GO:0010736) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
retinoic acid-responsive element binding (GO:0044323) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
sterol response element binding (GO:0032810) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
E-box binding (GO:0070888) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
estrogen response element binding (GO:0034056) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
carbohydrate response element binding (GO:0035538) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
juvenile hormone response element binding (GO:0070594) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
cAMP response element binding (GO:0035497) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
N-box binding (GO:0071820) [is_a relation] is_a  RNA polymerase II cis-regulatory region sequence-specific DNA binding
None.