Term Information

Accession
GO:0000836
Name
Hrd1p ubiquitin ligase complex
Ontology
cellular_component
Synonyms
HRD1 ubiquitin ligase complex
Alternate IDs
None
Definition
A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78). Source: PMID:16619026, PMID:21454652, GOC:bf, PMID:16873066, GOC:elh
Comment
None
History
See term history for GO:0000836 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of Hrd1p ubiquitin ligase complex (GO:0000836)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Hrd1p ubiquitin ligase complex [is_a relation] is_a  ER ubiquitin ligase complex (GO:0000835)
Children of Hrd1p ubiquitin ligase complex (GO:0000836)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
Hrd1p ubiquitin ligase ERAD-M complex (GO:0000838) [is_a relation] is_a  Hrd1p ubiquitin ligase complex
Hrd1p ubiquitin ligase ERAD-L complex (GO:0000839) [is_a relation] is_a  Hrd1p ubiquitin ligase complex
None.