Term Information

Accession
GO:0000394
Name
RNA splicing, via endonucleolytic cleavage and ligation
Ontology
biological_process
Synonyms
mRNA splicing
Alternate IDs
None
Definition
Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. Source: GOC:krc, ISBN:0879695897
Comment
Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
History
See term history for GO:0000394 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
RNA splicing, via endonucleolytic cleavage and ligation [is_a relation] is_a  RNA splicing (GO:0008380)
Children of RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA splicing, via endonucleolytic cleavage and ligation (GO:0070054) [is_a relation] is_a  RNA splicing, via endonucleolytic cleavage and ligation
RNA exon ligation (GO:0000378) [BFO:0000050 relation] BFO:0000050  RNA splicing, via endonucleolytic cleavage and ligation
tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) [is_a relation] is_a  RNA splicing, via endonucleolytic cleavage and ligation
None.