Term Information

Accession
GO:0000373
Name
Group II intron splicing
Ontology
biological_process
Synonyms
mRNA splicing
Alternate IDs
None
Definition
The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Source: GOC:krc, PMID:11377794
Comment
Note that Group II introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; and mRNA of bacteria.
History
See term history for GO:0000373 at QuickGO
Subset
None
Feedback
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Parents of Group II intron splicing (GO:0000373)
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Group II intron splicing [is_a relation] is_a  RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)

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