Term Information

Accession
GO:0000347
Name
THO complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. Source: GOC:krc, PMID:16983072, PMID:11979277, PMID:11060033
Comment
None
History
See term history for GO:0000347 at QuickGO
Subset
goslim_pir
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of THO complex (GO:0000347)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
THO complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
Children of THO complex (GO:0000347)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nucleoplasmic THO complex (GO:0000446) [is_a relation] is_a  THO complex
THO complex part of transcription export complex (GO:0000445) [is_a relation] is_a  THO complex
None.