Term Information

Accession
GO:0000252
Name
C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
Ontology
molecular_function
Synonyms
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating), 3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating), 3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating), 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity, C-3 sterol dehydrogenase (C-4 decarboxylase) activity, C-3 sterol dehydrogenase activity, sterol 4alpha-carboxylic decarboxylase activity, sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity, sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
Alternate IDs
None
Definition
Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H. Source: PMID:9811880, EC:1.1.1.170
Comment
Note that zymosterol is cholesta-8,24-dien-3-ol.
History
See term history for GO:0000252 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity (GO:0000252)
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C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity [is_a relation] is_a  oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

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