Term Information

Accession
GO:0000224
Name
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
Ontology
molecular_function
Synonyms
PNGase, N-glycanase activity, N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity, N-oligosaccharide glycopeptidase activity, PNGase A, PNGase F, peptide:N-glycanase, jack-bean glycopeptidase, glycopeptidase activity, glycopeptide N-glycosidase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue. Source: EC:3.5.1.52
Comment
None
History
See term history for GO:0000224 at QuickGO
Subset
None
Feedback
Comments, changes to terms, or requests for new ontology terms can be made at GO issue tracker on GitHub.

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Parents of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (GO:0000224)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity [is_a relation] is_a  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)

This term has no children.

EC
3.5.1.52
MetaCyc
3.5.1.52-RXN
Reactome
R-HSA-8850594