DNA gyrase inhibitor, DNA gyrase inhibitors, DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitor, DNA topoisomerase (ATP-hydrolysing) (EC 5.99.1.3) inhibitors, DNA topoisomerase (ATP-hydrolysing) inhibitor, DNA topoisomerase (ATP-hydrolysing) inhibitors, DNA topoisomerase II inhibitor, DNA topoisomerase II inhibitors, EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitor, EC 5.99.1.3 (DNA topoisomerase (ATP-hydrolysing)) inhibitors, EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitors, EC 5.99.1.3 inhibitor, EC 5.99.1.3 inhibitors, inhibitor of type II topoisomerase, inhibitors of type II topoisomerase, topoisomerase II inhibitor, topoisomerase II inhibitors, topoisomerase-II inhibitor, topoisomerase-II inhibitors, type II DNA topoisomerase inhibitor, type II DNA topoisomerase inhibitors
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Definition
A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
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